Postnatal growth restriction, feeding tolerance
Conditions
Interventions
Group 1: Breast milk fortification with a fortifier based on donor's milk
Group 2: Breast milk fortification with the current standard fortifier
Sponsors
Paracelsus Medizinische Privatuniversität, Klinikum Nürnberg, Klinik für Neugeborene, Kinder und Jugendliche
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: -Preterm infants receiving fortified breast milk.
Exclusion criteria
Exclusion criteria: -Gastrointestinal malformation, severe congenital anomalies, and chromosomal abnormalities; -Preterm infants with enterostomy or short bowel syndrome; -Sepsis - All infants with gram-negative sepsis are excluded for per protocol analysis. -Necrotizing enterocolitis defined by food intolerance associated with positive radiographic findings (pneumatosis intestinalis - Bell stage 2; air in the biliary tract or free air in the peritoneum - Bell stage 3).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Weight measured with a scale at a postmenstrual age of 36 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Growth, nutritional intake, feeding tolerance, clinical chemstry, morbidity, length of stay | — |
Countries
Germany
Contacts
Public ContactChristoph Fusch
Paracelsus Medizinische Privatuniversität, Klinikum Nürnberg, Klinik für Neugeborene, Kinder und Jugendliche
Outcome results
None listed