J80.0
Conditions
Interventions
Group 1: Pulse Contour Cardiac Output (PiCCO) monitoring and echocardiographies will be performed in 20 patients with ARDS at 5 time points (0, 2, 6, 24, and 26h hours after study inclusion) each afte
Sponsors
Universitätsklinik Heidelberg
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Consent by the consultant physician procedure ("Giessen model") or consent of the legal representative - Invasive ventilation - Diagnosis "ARDS" according to Berlin definition - Ventilation in TCAV protocol
Exclusion criteria
Exclusion criteria: - Failure to meet inclusion criteria - Contraindications for ventilation in the TCAV protocol: Obstructive Ventilatory Disorder, Undrained Pneumothoraces. - Refusal to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaulation of the influence of TCAV on hemodynamics using echocardiography and PiCCO monitoring. At 0, 2, 6, 24, and 26 hours after study inclusion, respectively. | — |
Secondary
| Measure | Time frame |
|---|---|
| Flow cytometry for T-/B- and NK-cells, RNA analysis, 30-day survival. At 0, 6, and 24 hours after study inclusion, respectively. | — |
Countries
Germany
Contacts
Public ContactPatrick Rehn
Universtätsklinik Heidelberg
Outcome results
None listed