D66 D67
Conditions
Interventions
Group 1: Patients with hemophilia A or B
Periodontal examination (plaque index, probing pocket depth, recessions). Gingival bleeding will be assessed and compared as bleeding on probing (BOP) and ging
Sponsors
Zentrum der Zahn-, Mund- und Kieferheilkunde (Carolinum) der Johann Wolfgang Goethe-Universität Frankfurt am Main
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - written informed consent - Test (patients): hemophilia A or B Control (probands): no heritary bleeding disorders or medication that interfer with hemostasis
Exclusion criteria
Exclusion criteria: - disease or condition (e.g., heart valve prothesis) that requires antibiotic prophylaxis for measures (assessment of periodontal probing parameters) causing transitory bacteriemia - additional bleeding disorder - intake of drugs that interfere with hemostasis (e.g., ASS)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| bleeding on probing (BOP): approximatly 30 seconds after assessment of probing pocket depths using a Florida probe (6 sites per tooth: mesio-buccal, centro-buccal, disto-buccal, disto-oral, centro-oral, mesio-oral) assessment whether the respective sites bleed or not. | — |
Secondary
| Measure | Time frame |
|---|---|
| Gingival Bleeding Index (GBI): a periodontal probe (PCPUNC15, HuFriedy) is run along the gingival margin (maxilla buccal, maxilla oral, mandible buccal, mandible oral) and scored at 6 sites per tooth (mesio-buccal, centro-buccal, disto-buccal, disto-oral, centro-oral, mesio-oral) whether the respective sites bleed or not. | — |
Countries
Germany
Contacts
Public ContactPeter Eickholz
Zentrum der Zahn-, Mund- und Kieferheilkunde (Carolinum) der Johann Wolfgang Goethe-Universität Frankfurt am Main
Outcome results
None listed