Evaluation of the peri-implant gingiva perfusion using laser Doppler flowmetry and tissue spectrophotometry- A prospective controlled study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00032148

Enrollment

Registered

2023-07-24

Start date

2023-07-06

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Z96.5

Interventions

Group 1: Measurement of the periimplant perfusion of implants placed in local bone with Laser-Doppler flowmetry and tissue spectrophotometry Group 2: Measurement of the periimplant perfusion of Implan

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: In order to be included in the study, the patient must present himself/herself to the clinic of the Clinic for Oral and Maxillofacial Surgery in Aachen as part of the regular implant recall program. The group assignment is then controlled depending on the bone site in which the inserted implants are located: Group 1 includes the patients with implants in the local bone, Group 2 includes the implants in the avascularly augmented bone and Group 3 includes the patients Patients whose implants were placed in a microvascular graft (microvascular anastomosed iliac crest or fibula grafts).

Exclusion criteria

Exclusion criteria: The exclusion criteria are patients with an acute intraoral abscess, minors, pregnant women and patients taking antibiotics or drugs that affect blood flow or the physiological state of the intraoral mucous membranes.

Design outcomes

Primary

Measure	Time frame
The aim of this prospective controlled clinical study is to determine value limits for various perfusion parameters such as peri-implant hemoglobin concentration and oxygen saturation as well as blood flow and to compare these with the clinical examination results of patients with implants in different bone sites. After completing the examination of 20 patients with implants in local bone, 20 patients whose implants are in avascular transplants and 20 patients with implants in microvascular transplants, the values of the clinical examinations are compared with the results of the perfusion measurements and correlations are determined.	—

Measure

Time frame

The aim of this prospective controlled clinical study is to determine value limits for various perfusion parameters such as peri-implant hemoglobin concentration and oxygen saturation as well as blood flow and to compare these with the clinical examination results of patients with implants in different bone sites. After completing the examination of 20 patients with implants in local bone, 20 patients whose implants are in avascular transplants and 20 patients with implants in microvascular transplants, the values of the clinical examinations are compared with the results of the perfusion measurements and correlations are determined.

—

Secondary

Measure	Time frame
Evaluation of the perfusion-related and clinical values.	—

Countries

Germany

Contacts

Public ContactMarie Sophie Katz

Klinik für Mund-Kiefer- und Gesichtschirurgie der Uniklinik RWTH Aachen

mkatz@ukaachen.de0241-8088258

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026