G30.9
Conditions
Interventions
Group 1: No special assessments are required in this study. Only retrospective data available at hospital clinical charts is collected.
Sponsors
Eli Lilly and Company Ltd
Eligibility
Sex/Gender
All
Age
55 Years to No maximum
Inclusion criteria
Inclusion criteria: • Adult patients >55 years of age at diagnosis; • newly diagnosed with probable AD; • with a Mini-Mental State Examination (MMSE) [22] score of =20 and =28 at diagnosis; • and presented within the normal course of care; • to have visited for the first time the participating center from 15 years to 4 years before the date of data collection.
Exclusion criteria
Exclusion criteria: • Patients with a history, clinical signs or imaging of stroke or transient ischemic attack. • Patients with a history of Parkinson’s disease prior to, or at the start of AD onset. • Patients with frontotemporal dementia. • and patients with probable Lewy-body disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary objective of this study is to describe the course of AD in terms of worsening in cognitive function in an incidence sample of AD patients. Period between 5-15 past years. The time required to collect data is between 3-5 hours per patient. | — |
Secondary
| Measure | Time frame |
|---|---|
| • To describe the patient characteristics at the diagnosis of AD, overall and by the severity of AD. • To describe the course of AD in terms of worsening in basic and instrumental activities of daily living in an incidence sample of AD patients, overall and by the severity of AD. • To describe the course of AD in terms of the presence of behavioral symptoms in an incidence sample of AD patients, overall and by the severity of AD. • To describe profiles of patients as a function of increase of severity of AD in terms of worsening in cognitive function and basic and instrumental activities of daily living. • To describe the main use of services of patients with AD (hospitalization, outpatient visits, and institutionalization). • To estimate the duration of AD from diagnosis to institutionalization or death as a function of disease severity. | — |
Countries
France, Germany, Italy, Spain, United Kingdom
Outcome results
None listed