M81.9 M85.9
Conditions
Interventions
Group 1: Patients with existing quantitative computed tomography (QCT) and routine CT covering the spine.
Sponsors
Klinikum rechts der Isar der Technischen Universität München
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - QCT and routine CT available. - Maximum interval between QCT and routine CT of 30 days. - All underlying diseases except for multiple myeloma. - At least one vertebral body covered from TH12-L4, which is captured by QCT as well as routine CT and can be measured (i.e., no fracture, no foreign material/cement within the vertebral body). - Availability of raw data (axial with max. slice thickness of 1 mm) and/or sagittal reconstruction of the spine (sagittal with max. slice thickness of 3 mm) for routine CT.
Exclusion criteria
Exclusion criteria: - Known diagnosis of multiple myeloma. - Raw data with slice thickness > 1 mm and/or sagittal reconstruction of the spine with slice thickness > 3 mm for routine CT.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Opportunistically determined volumetric bone mineral density (vBMD) values show comparable or superior performance in comparison to QCT for the discrimination of patients with vs. without vertebral fractures. | — |
Secondary
| Measure | Time frame |
|---|---|
| Opportunistically determined vBMD values show superior agreement with QCT-based vBMD when compared to standard measurements of Hounsfield Units (HU) regarding the classification of patients with osteoporosis/osteopenia/normal bone density. | — |
Countries
Germany
Contacts
Public ContactNico Sollmann
Klinikum rechts der Isar der Technischen Universität München
Outcome results
None listed