Cognitive Impairment and Fatigue after SARS-CoV-2: EEG study for the identification of biomarkers

Cognitive Impairment and Fatigue after SARS-CoV-2: EEG study for the identification of biomarkers - EPOC

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00032132

Enrollment

100

Registered

2023-06-26

Start date

2023-07-05

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cognitive impariment and fatigue

Interventions

Group 1: For subjects participating in the COVIDOM study follow-up, this additional study will assess brain activity by recording an electroencephalogram (EEG) once. The cohort will be people who were

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: No additional inclusion criteria

Exclusion criteria

Exclusion criteria: No Exclusion criteria

Design outcomes

Primary

Measure	Time frame
Event-related potentials (P300, P1, C1, N1, P2) and power spectra (delta, theta, alpha, beta, gamma) from the EEG signal during the processing of neuropsychological test procedures (oddball paradigm, redundant target effect, n-back task, psychomotor vigilance task) or at rest. In addition, a questionnaire for self-assessment of current fatigue symptomatology (FACIT-F)	—

Secondary

Measure	Time frame
Behavioral measures (reaction times, errors, missings) from neuropsychological testing procedures (trail making test, oddball paradigm, redundant target effect, n-back task, psychomotor vigilance task) and effects over time as well as other psychiatric questionnaires (HADS-D, PSQI)	—

Countries

Germany

Contacts

Public ContactWalter Maetzler

Universitätsklinikum Schleswig-Holstein, Campus Kiel, Neurogeriatrie

w.maetzler@neurologie.uni-kiel.de0431 500-23981

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026