Prognosis of Acute Symptomatic Seizures in Neurosurgery

Prognosis of Acute Symptomatic Seizures in Neurosurgery - PROSE-NS

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00032119

Enrollment

120

Registered

2023-06-21

Start date

2023-09-14

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G40.5

Interventions

Group 1: Following an acute symptomatic first-ever epileptic seizure, participants will be followed up for 5 years and interviewed regarding seizure relapse, seizure-related hospitalisation, anti-seiz

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Acute symptomatic, first-ever epileptic eizure due to traumatic brain injury, subdural haematoma, or intracranial surgery

Exclusion criteria

Exclusion criteria: Status epilepticus

Design outcomes

Primary

Measure	Time frame
Occurrence and time point of a first unprovoked epileptic seizure relapse within 12 months of the acute symptomatic first-ever seizure.	—

Secondary

Measure	Time frame
Occurrence and time point of a first unprovoked epileptic seizure relapse within 5 years of the acute symptomatic first-ever seizure; occurrence and time point of additional acute symptomatic seizures; use of anti-seizure medication; seizure-related rehospitalisation; overall functional outcome (Glasgow Outcome Score Extended); EEG findings.	—

Countries

Germany, Switzerland

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: May 1, 2026