Evaluation of motor recovery after stroke with indication for early rehabilitation.-Definition of prognostic factors and medical economic analysis

Evaluation of motor recovery after stroke with indication for early rehabilitation.-Definition of prognostic factors and medical economic analysis - Cologne stroke registry (CSR)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00032100

Enrollment

116

Registered

2023-08-15

Start date

2023-03-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I61 I63 I64

Interventions

Group 1: The observation group of the Clinic and Polyclinic for Neurology, University Hospital Cologne comprises 150 patients. These will be included in the study at three time points after informed c

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: First ever Stroke (ICD: I61, I63, I64) NIHSS acute >0 Points Frühreha-Barthel-Index <30 points Clinical onset of symptoms in the last 72 hours

Exclusion criteria

Exclusion criteria: Subarachnoid hemorrhage (SAB), traumatic brain injury, hemorrhage into preformed cavities, other brain pathology significantly affecting prognosis (e.g., tumor, metastases). Other disease determining the prognosis (e.g., acute myocardial infarction, endocarditis, cancer, multiple sclerosis) Barthel index 30 points or above (thus not suitable for phase B) Planned surgical procedures in the next 3 months Cognitive impairment that makes informed consent impossible Death as a result of the disease up to T1 Lack of patient compliance Lack of informed consent from patient or relatives

Design outcomes

Primary

Measure	Time frame
The primary endpoint of the study is the motor function recovery after stroke, within the first 6 months of rehabilitation. For this purpose, a physical examination will be performed at three time points (T0, T1, T2). This includes the Fugl-Meyer Assessment and the following scales: Barthel-Index, NIHSS, mRS, FIM and FAM. T0 represents the time of study inclusion, here the patient is examined after consent on the stroke unit within the first 48 hours after stroke. T1 defines the time at the end of the early rehabilitation in the Department of Neurology, University Hospital Cologne. T2: represents the follow-up date after 6 months in the Polyclinic for Neurology, University Hospital Cologne.	—

Measure

Time frame

The primary endpoint of the study is the motor function recovery after stroke, within the first 6 months of rehabilitation. For this purpose, a physical examination will be performed at three time points (T0, T1, T2). This includes the Fugl-Meyer Assessment and the following scales: Barthel-Index, NIHSS, mRS, FIM and FAM. T0 represents the time of study inclusion, here the patient is examined after consent on the stroke unit within the first 48 hours after stroke. T1 defines the time at the end of the early rehabilitation in the Department of Neurology, University Hospital Cologne. T2: represents the follow-up date after 6 months in the Polyclinic for Neurology, University Hospital Cologne.

—

Secondary

Measure	Time frame
Healtheconomic evaluation of rehabilitation after stroke, after 6 months	—

Countries

Germany

Contacts

Public ContactMichael Schroeter

Klinik und Poliklinik für Neurologie, Uniklinik Köln

michael.schroeter@uk-koeln.de022147887239

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026