C22.0 C78.7
Conditions
Interventions
Group 1: The randomization list is kept at the study center of the Department of Radiology. The procedure will be performed during an inpatient stay or on an outpatient basis.
1st intervention arm (go
Sponsors
LMU München
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Clinical indication for image-guided liver biopsy. The indication for image-guided intervention in this case must be independent of the study presented. - Maximum focal size 2 cm - No contraindication to MRI examination or CT examination with the respective contrast agent. - Platelets >50,000/mm3 (50 GPt/l) - PTT-INR/PTT 18 years
Exclusion criteria
Exclusion criteria: - Lack of consent and/or lack of capacity to consent to the study. - Contraindications for an MRI examination, especially implants not suitable for MR, tattoos or piercings, limiting claustrophobia - Contraindications for a CT examination - Contraindications for contrast media: o Known allergy to MR or CT contrast agents. o Higher grade renal insufficiency (GFR 1.5 times upper normal value o Presence of a coagulation abnormality
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recording of the clinical success rate (hit rate) of the liver lesion demonstrated either by the positive result in the histopathological examination of the punch biopsy (correlating to the known tumor entity) or by a confirmation of the negative result in the histopathological examination by the imaging result in the follow-up MRI examination after 3 months. | — |
Secondary
| Measure | Time frame |
|---|---|
| - To assess the technical success rate of MR-guided biopsy compared to CT-guided biopsy. - To assess the complication rate of MR-guided biopsy compared to CT-guided biopsy. - Survey of the duration of the procedure in MR-guided biopsy compared to that under CT-guidance. | — |
Countries
Germany
Contacts
Public ContactMax Seidensticker
LMU
Outcome results
None listed