Surgical diseases of the pancreatic head, in particular pancreatic cancer.
Conditions
Interventions
Group 1: Prospective collection of microbiome samples and clinical data from patients undergoing Whipple's surgery.
Sponsors
Klinik für Allgemein-, Viszeral- und Transplantationschirurgie, Ludwig-Maximilians-Universität (LMU) München
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Patients with resectable tumor of the pancreas scheduled for tumor resection, especially of the head of the pancreas, i - Ability to consent at the time of inclusion in the study - Must be of legal age at the time of admission to the study
Exclusion criteria
Exclusion criteria: - Inability to consent or underage at the time of inclusion in the study. - Mental or physical disorders that could affect informed consent or treatment - Individuals with understanding/language problems or inability to comply with study and/or follow-up procedures - Any contraindication to surgery - Acute or ongoing episode of pancreatitis (clinical symptoms of pancreatitis, elevated lipase and/or CRP levels, radiological or intraoperative signs of acute pancreatitis)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prospective analysis of the microbiome in pancreatic head resection and its influence on subtyping, tumor growth and therapy resistance in pancreatic carcinoma. | — |
Secondary
| Measure | Time frame |
|---|---|
| 30-day mortality, morbidity, length of hospital stay, initiation of systemic therapy, and oncologic outcomes in cancer patients. | — |
Countries
Germany
Contacts
Public ContactMatthias Ilmer
Klinik für Allgemein-, Viszeral- und Transplantationschirurgie
Outcome results
None listed