Determination of volume responsiveness in patients with acquired brain injury

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00032021

Enrollment

Registered

2023-06-09

Start date

2023-02-08

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with intracranial hemorrhage (spontaneous or traumatic)

Interventions

Group 1: Patients with intracranial hemorrhage (spontaneous or traumatic), continuous ICP monitoring

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Continuous ICP monitoring Continuous blood pressure monitoring

Exclusion criteria

Exclusion criteria: Refusal by the patient or their caregiver Absence of external ventricular drainage (EVD)/ICP probe No arterial cannula for continuous blood pressure measurement Pregnancy Persistent pathologically elevated intracranial pressure

Design outcomes

Primary

Measure	Time frame
Difference in ICP and MAP values between baseline (before testing is performed) and the maximum or minimum value	—

Secondary

Measure	Time frame
CPP, LVOT VTI, stroke volume, cardiac output and cardiac index	—

Countries

Germany

Contacts

Public ContactJan-Oliver Neumann

Universitätsklinikum Heidelberg, Neurochirurgische Klinik

Jan-Oliver.Neumann@med.uni-heidelberg.de+49 6221 56 38096

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026