Cardiovascular characteristics of the healthy children, adolescents and young adults during simulated short-term exposure to high altitude

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00032016

Enrollment

Registered

2023-06-09

Start date

2023-02-25

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Physiologic changes in healthy volunteers

Interventions

Group 1: Healthy volunteers will be examined once in room air and once under normobaric hypoxia corresponding to an altitude of 3500m above sea level following at least 30 minutes for equilibration.

Eligibility

Sex/Gender

All

Age

8 Years to 28 Years

Inclusion criteria

Inclusion criteria: healthy volunteers

Exclusion criteria

Exclusion criteria: Significant heart, lung, rheumatological or oncological disorders. Patients who are unable to provide informed consent or are not able to participate in spiroergometry.

Design outcomes

Primary

Measure	Time frame
It is the aim of this study to evaluate the acute effect of normobaric hypoxia on heart and vasculature (arterial stiffness, microcirculation) in health children and young adults age 8-28 years, using a multimodal approach. - right ventricular pressure and function	—

Secondary

Measure	Time frame
- Left ventricular SF, E', E/E' - VO2 - central Blutdruck, Augmentation index, Pulse Wave Velocity - Aging index - retinal arteriolar-to-venular diameter ratio (AVR) (static retinal analyser)	—

Countries

Germany

Contacts

Public ContactConstance Weismann

Ludwig Maximilian Universität

constance.weismann@med.uni-muenchen.de004989 440073941

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026