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Muscle atrophy in polytrauma patients

Muscle atrophy in polytrauma patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00032012
Enrollment
10
Registered
2023-06-02
Start date
2023-04-17
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

T03 T02 T01 T06

Interventions

Group 1: Patients with fractures treated conservatively or surgically should have longitudinal measurements of muscle blood flow, muscle thickness, muscle fibre length, muscle fibre angle, subcutaneou

Sponsors

Universität des Saarlandes
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: - 18 years and older - Bone fracture - Written and verbal consent in the case of capacity to consent, or consent by a guardian

Exclusion criteria

Exclusion criteria: - Lack of consent - Age under 18 years

Design outcomes

Primary

MeasureTime frame
The primary endpoints are muscle atrophy rate, time of minimum, recovery rate and measured or calculated time of muscular recovery. These characteristics are assessed using the following parameters, which are measured in the hospital at two-day intervals (if possible depending on the clinical condition) and later at follow-up appointments in the outpatient clinic up to a maximum of 3 months after injury: 1. muscle thickness 2. muscle strength 3. muscle perfusion (SO2, Hb, blood flow) 4. muscle fibre length 5. muscle fibre angle 6. thickness of subcutaneous tissue The following measuring devices are used for this purpose: 1. a handgrip strength dynanometer 2. the Oxygen to See of LEA Medizintechnik to measure SO2, Hb and blood flow 3. an ultrasound device to measure muscle thickness, muscle fibre length, muscle fibre angle and the thickness of the subcutaneous tissue.

Secondary

MeasureTime frame
None. All parameters mentioned above are equally important.

Countries

Germany

Contacts

Public ContactBergita Ganse

Universität des Saarlandes

bergita.ganse@uks.eu+49 6841 16 31570

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026