U07.1
Conditions
Interventions
Group 1: Covid-19 infection during pregnancy and labor
= patients with via PCR proven SARS-CoV-2 infection during pregnancy or under labor with delivery 37 0/7 - 41 6/7 weeks of gestation.
Group 2: co
Sponsors
Klinikum im Friedrichshain
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: inclusion criteria Covid-19 patient group: a) Covid-19 infection during pregnancy inclusion criteria control group: a) gestational age 37 0/7 - 41 6/7 weeks of gestation b) uncomplicated pregnancy
Exclusion criteria
Exclusion criteria: exclusion criteria Covid-19 patient group: a) minor of age b) not capable of consent exclusion criteria control group: a) minor of age b) not capable of consent c) gestational or pre-existing diabetes mellitus d) placental insufficiency e) gestosis f) triple I
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| histoathological lesions of placental specimen concerning inflammation and hypercoagulopathy (pervillous fibrin deposit, infarction, intervillous thrombi, intervillositis) | — |
Secondary
| Measure | Time frame |
|---|---|
| • number of vaginal delivery, vaginal operative delivery, cesarean section • number of symptomatic Covid-19 infections • number of severe Covid-19 infections • number of placental insufficiency (defined as intrauterine growth restriction, oligohydramnios, abnormal fetal doppler ultrasound) • number of late miscarriages • number of intrauterine fetal death • number of premature abruption of the placenta • number of occurrence of preeclampsia secondary criteria: • maternal age • maternal comorbidities • gestational age at time of delivery • gestational age at the time of the Covid-19 illness • type of Covid-19 symptoms | — |
Countries
Germany
Contacts
Public ContactJulia Kummer
Klinikum im Friedrichshain
Outcome results
None listed