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Observational study/ pilot study of cyclophotocoagulation in advanced glaucoma

Observational study/ pilot study of cyclophotocoagulation in advanced glaucoma

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00031874
Enrollment
70
Registered
2023-07-11
Start date
2023-07-17
Completion date
Unknown
Last updated
2025-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

H40

Interventions

Group 1: Group 1: Transcleral continuous wave cyclophotocoagulation applying 20 foci for 2 seconds at 2 watts. Intraocular pressure will be measured postoperatively at 1, 3, 5 and 20 hours and RNFL,

Sponsors

Medizinische Hochschule Hannover
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Chronic open angle glaucoma, narrow angle glaucoma, PEX glaucoma, pigment dispersion glaucoma - Conservatively not adjustable glaucoma - Need for treatment by cyclophotocoagulation - Measurability of retinal nerve fiber layer thickness (RNFL) by optical coherence tomography - Minimum age 18 years, gender male/female

Exclusion criteria

Exclusion criteria: - Already treated with cyclophotocoagulation - Normal pressure glaucoma, congenital glaucoma, rubeotic glaucoma, low eye pressure preoperatively - Lack of ability to consent to the study

Design outcomes

Primary

MeasureTime frame
Elevation of intraocular pressure in the first five hours after intervention (>20% above baseline)

Secondary

MeasureTime frame
- intraocular pressure reduction (<20%) nach 3 Monaten - RNFL after 3 month - topical glaucoma treatment after 3 month - macula edema within 3 month - postoperative inflammatory stimulus after 20h - therapy satisfaction after 3 month - impact of iris color/ skin color/ hair color on postoperative intraocular pressure

Countries

Germany

Contacts

Public ContactMigle Lindziute

Universitätsklinik für Augenheilkunde der Medizinischen Hochschule Hannover

Lindziute.Migle@mh-hannover.de+49 511 532 4627

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026