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Preliminary study on the role of local chronic inflammation in persistent work-related complaints in the arm/hand area during heavy occupational stress

Preliminary study on the role of local chronic inflammation in persistent work-related complaints in the arm/hand area during heavy occupational stress - LINOS

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00031872
Enrollment
40
Registered
2023-05-25
Start date
2024-12-19
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Z87.3

Interventions

Group 1: Exposed group: Twenty workers (10 women, 10 men) who are exposed to stressful occupational activities of the hands (e.g., upholsterer as profession) and who report minor to severe recurrent p

Sponsors

Institut für Arbeitsmedizin, Sozialmedizin und Versorgungsforschung, Universitätsklinikum Tübingen
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Employment: a minimum of one year employment to above described workplaces at the time of study inclusion. Musculoskeletal pain: the study population should suffer from varying degrees of musculoskeletal pain in the elbow/forearm/hand-area, which will be assessed using the Cornell Musculoskeletal Discomfort Questionnaire (Kreuzfeld et al. 2016).

Exclusion criteria

Exclusion criteria: Status after accident and/or systemic diseases that affect joints or muscles and/or are associated with acute and chronic inflammations. Musculoskeletal pain that is not localized in the elbow/forearm/hand-area and that is equally or more severe than in the elbow/forearm/hand-area examined in the current study, as assessed by the Cornell Musculoskeletal Discomfort Questionnaire (Kreuzfeld et al., 2016). Relative and absolute contraindications for repeated blood sampling, such as: fear of blood sampling (relative), taking anticoagulants (absolute), few suitable veins that should only be used for therapeutic interventions (absolute).

Design outcomes

Primary

MeasureTime frame
Reliability of the inflammatory biomarkers (i.a.) IL-1ß, IL-6 and CRP

Secondary

MeasureTime frame
Musculoskeletal upper-extremity pain Clinical signs of chronic musculoskeletal upper-extremity disorders

Countries

Germany

Contacts

Public ContactTessy Luger

Arbeitsphysiologisches Labor, Institut für Arbeitsmedizin, Sozialmedizin und Versorgungsforschung

Tessy.Luger@med.uni-tuebingen.de+4970712984364

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026