All patients undergoing a pancreatic resection.
Conditions
Interventions
Group 1: All patients undergoing pancreatic resections (without one-stage total pancreatectomy) in the participating hospitals which consent into the participation of this trial.
Sponsors
Universitätsklinikum Carl Gustav Carus
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - All patients undergoing pancreatic resection for malignant and benign disease with or without pancreatic anastomosis - Patients aged 18-85 years - Willingness to participate as demonstrated by giving a written informed consent.
Exclusion criteria
Exclusion criteria: - Necrosectomy (endoscopic or open) for primary acute pancreatitis or within laparotomy - Age less than 18 years - Surgical drainage procedures without pancreatic resection (cystojejunostomy for pancreatic pseudocysts) - One-stage total pancreatectomy - Missing written consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - To evaluate the incidence and assess the value of postoperative biochemical changes for PPAP in short-term outcome (incidence and severity of complications represented in the Clavien-Dindo Classification (CDC) and Comprehensive Complication Index (CCI)). - To confirm and complement the definition and classification of postoperative acute pancreatitis (PPAP) of the international study group of pancreatic surgery (ISGPS). | — |
Secondary
| Measure | Time frame |
|---|---|
| - To evaluate postpancreatectomy biochemical changes (lipase, white blood cells (WBC), CRP) and their clinical significance for the postoperative course. - To develop clinical scores for predicting severe postoperative complications after pancreatic resection. - To provide knowledge for effective early management of complications to reduce morbidity | — |
Countries
Germany
Contacts
Public ContactOlga Radulova-Mauersberger
Universitätsklinikum Carl Gustav Carus
Outcome results
None listed