Investigation of the ventilation distribution in the lungs of healthy subjects depending on body position and positive airway pressure

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00031859

Enrollment

Registered

2023-10-05

Start date

2023-10-05

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventilation distribution in the lung under extreme body positioning

Interventions

Group 1: Spontaneous breathing with and without support from continuous airway pressure in two levels (5 and 10 mbar) and in seven body positions (breathing for 3 minutes per pressure support level an

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Healthy adult individuals without cardiovascular pre-existing conditions.

Exclusion criteria

Exclusion criteria: Known respiratory or cardiac disease, pregnancy, lack of consent, obesity (BMI > 30), pacemaker, implantable cardioverter, defibrillator or other active implants, known heart defects, performance-limiting heart failure, glaucoma or increased intraocular pressure due to other causes

Design outcomes

Primary

Measure	Time frame
Ventilation inhomogeneity of the lungs as measured by electrical impedance tomography for each continuous pressure support level and each body position	—

Secondary

Measure	Time frame
ventilated lung area and regional ventilation distribution as measured by electrical impedance tomography for each continuous pressure support level and each body position	—

Countries

Germany

Contacts

Public ContactSilke Borgmann

Uniklinikum Freiburg

silke.borgmann@uniklinik-freiburg.de+49 761 270 23290

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026