Effects of Extracorporeal Shockwave Therapy on new bone formation in a biomimetic in-vitro bone-block model

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00031829

Enrollment

Registered

2025-03-11

Start date

2023-05-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

E66

Interventions

Group 1: Control (no treatment) Group 2: Treatment of the bone block with extracorporeal shock waves on days 14 and 28 after colonization of the bone blocks (500 impulses, frequency 5 Hz, 2.5 bar). Gr

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients having a liposuction for lipoaugmentation

Exclusion criteria

Exclusion criteria: No approval, severe systemic diseases, chemotherapy, tumor disease

Design outcomes

Primary

Measure	Time frame
Bone formation (Giemsa-Toluidine Blue staining, histological quantification of newly formed bone within the bone block).	—

Secondary

Measure	Time frame
Amount of secreted alkaline phosphatase, osteocalcin, osteopontin, collagen I (measured by ELISA, every 3 days throughout the entire cultivation period).	—

Countries

Germany

Contacts

Public ContactDiana Heimes

Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie der Universitätsmedizin Mainz

Diana.heimes@unimedizin-mainz.de006131 17 5086

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026