E84
Conditions
Interventions
Group 1: Collecting clinical data and samples from patients with cystic fibrosis in a registry and a DNA- and biobank.
Sponsors
Universitätsklinikum Heidelberg
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Confirmed diagnosis of cystic fibrosis
Exclusion criteria
Exclusion criteria: All persons who or whose parents refuse to participate or exercise their right to withdraw, or who are uncertain about the diagnosis of cystic fibrosis, will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Establishment of a bio- and DNA bank for current and future research projects as well as establishment of a registry with the essential clinical data of patients with cystic fibrosis for correlation with disease-modifying genes, new biomarkers and (new) cystic fibrosis pathogens for current and future research projects. | — |
Secondary
| Measure | Time frame |
|---|---|
| - Identification of polymorphisms in disease-modifying genes that influence the clinical course of patients with cystic fibrosis. - Identify new biomarkers to improve diagnostics, monitor disease progression and verify treatment response. - Investigate the pathogenesis of pulmonary infection in cystic fibrosis using airway secretion samples and epithelial function using nasal epithelial cells. - Identification of new therapeutic targets. | — |
Countries
Germany
Contacts
Public ContactIris Kühbandner
Universitätsklinikum Heidelberg
Outcome results
None listed