The influence of the biographic-narrative approach according to the Narraktiv protocol by Corsten et al. (2015) on the quality of life of people with primary progressive aphasia

The influence of the biographic-narrative approach according to the Narraktiv protocol by Corsten et al. (2015) on the quality of life of people with primary progressive aphasia - Cope PPA

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00031782

Enrollment

Registered

2024-01-26

Start date

2024-02-07

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Progressive Aphasia G31.0 F02.0

Interventions

Group 1: Cope PPA therapy: The therapy is based on the Narraktiv® protocol, which was adapted following the evaluation of the focus group interview (Corsten et al., 2015

Corsten & Hardering, 2015). After an initial interview and pre-test, all participants take part in a total of five individual and seven group therapies of 90 minutes each. The first three individual t

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: PPA diagnosis according to the consensus criteria of Gorno-Tempini (2011), all variants of PPA (logopenic variant, semantic variant and agrammatic variant) Group ability Ability to consent Intact visual acuity / sufficient acoustic comprehension (with hearing aid / visual aid)

Exclusion criteria

Exclusion criteria: Severe depressive symptoms (>35 points in the MADRS) Pronounced cognitive deficits (<10 points in the MMSE)

Design outcomes

Primary

Measure	Time frame
Improving the quality of life: - 39-item version of the Stroke and Aphasia Quality of Life Scale (SAQOL-39, Hilari et al., 2003) Measurement times: t0, t1, t2, t3	—

Secondary

Measure	Time frame
Changes in cognitive and linguistic functions: - Satisfaction with Life Scale (SWLS, Diener et al., 1985); aim: to measure life satisfaction, also in contrast to quality of life; measurement times: t0, t1, t2, t3 - Montgomery-Asberg Depression Scale (MADRS, Davidson et al., 1986); aim: to measure depression, also in relation to quality of life; measurement times: t0, t1, t2, t3 - Mini-Mental Status Test (MMST, Folstein et al., 1975); aim: to assess cognitive abilities; measurement times: t0, t1, t2, t3 - Scenario Test (ST, Nobis-Bosch, 2020); aim: to assess communicative-pragmatic abilities; measurement times: t0, t1, t2, t3 - Visual Analogue Scale (VAS, Ushijima et al., 2006); aim: to assess the mood of the participants; measurement times: before and after the 1st and 5th individual therapy sessions; after the 1st and 7th group therapy sessions - Semi-structured interview after the intervention; aim: to record attitudes towards / experiences with the intervention provided; measurement time: after the intervention - Fidelity checklist (self-rating); objective: self-reflection with regard to adherence to the customised Narraktiv® protocol after each individual and group therapy session - Fidelity checklist (independent rating); objective: quality assurance; evaluation of treatment adherence to the adapted Narraktiv® protocol after completion of the study in a randomised sample of 10% of the video recordings; measurement time: after completion of the study	—

Measure

Time frame

Changes in cognitive and linguistic functions: - Satisfaction with Life Scale (SWLS, Diener et al., 1985); aim: to measure life satisfaction, also in contrast to quality of life; measurement times: t0, t1, t2, t3 - Montgomery-Asberg Depression Scale (MADRS, Davidson et al., 1986); aim: to measure depression, also in relation to quality of life; measurement times: t0, t1, t2, t3 - Mini-Mental Status Test (MMST, Folstein et al., 1975); aim: to assess cognitive abilities; measurement times: t0, t1, t2, t3 - Scenario Test (ST, Nobis-Bosch, 2020); aim: to assess communicative-pragmatic abilities; measurement times: t0, t1, t2, t3 - Visual Analogue Scale (VAS, Ushijima et al., 2006); aim: to assess the mood of the participants; measurement times: before and after the 1st and 5th individual therapy sessions; after the 1st and 7th group therapy sessions - Semi-structured interview after the intervention; aim: to record attitudes towards / experiences with the intervention provided; measurement time: after the intervention - Fidelity checklist (self-rating); objective: self-reflection with regard to adherence to the customised Narraktiv® protocol after each individual and group therapy session - Fidelity checklist (independent rating); objective: quality assurance; evaluation of treatment adherence to the adapted Narraktiv® protocol after completion of the study in a randomised sample of 10% of the video recordings; measurement time: after completion of the study

—

Countries

Germany

Contacts

Public ContactMirjam Gauch

Universitätsmedizin

mirjam.gauch@unimedizin-mainz.de+49 06131 / 17-2474

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026