Zirconium used as synovial marker to detect loose knee prosthesis

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00031709

Enrollment

Registered

2023-04-18

Start date

2023-04-24

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

T84.4

Interventions

Group 1: During revision surgery of knee endoprostheses 1 ml synovial fluid is collected. The concentraction of zirconium is measured by inductively coupled plasma mass spectrometry. Two groups are

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Informed consent Indication for revision of a cemented knee prosthesis Initial use of a PMMA cement containing zirconium

Exclusion criteria

Exclusion criteria: patients < 18 years

Design outcomes

Primary

Measure	Time frame
Concentration of zirconium in the synovial fluid collected during revision surgery. The concentraction is measured by inductively coupled plasma mass spectrometry.	—

Countries

Germany

Contacts

Public ContactPhilip Anderson

König-Ludwig-Haus

p-anderson.klh@uni-wuerzburg.de0931/803-3135

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026