sex-specific differences of right heart size in patients with pulmonary arterial hypertension

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00031697

Enrollment

Registered

2023-04-25

Start date

2023-04-20

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I27.0

Interventions

Group 1: patients with pulmonary arterial hypertension

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: • Adult patients with PAH who are capable of giving consent • Patients with invasively confirmed PAH • Invasive, guideline-based diagnosed PAH: RHK: mPAP > 20 mmHg, PAWP = 15 mmHg, PVR =3 WU • Patients receiving drug therapy for the treatment of PAH.

Exclusion criteria

Exclusion criteria: • Underage patients • Patients who are incapable of giving consent • Pregnant patients • Relevant comorbidities that speak against the presence of PAH • Patients whose gender identity does not correspond to their biological sex

Design outcomes

Primary

Measure	Time frame
sex-specific differences in the right heart size meassured by RA- and RV-area, sex-specific differences in the RV-function at time of diagnosis (cross-sectional study) and follow up (about 6 months)	—

Secondary

Measure	Time frame
additional parameters of right heart size and right ventricular pump function change in right heart size during targeted therapy, correlation with other clinical parameters, sex-specific differences in right heart size during therapy (follow-up about 6 months after beginning of treatment)	—

Countries

Germany

Contacts

Public ContactEkkehard Grünig

Thoraxklinik Heidelberg gGmbH

ekkehard.gruenig@med.uni-heidelberg.de+49 6221 396 8053

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 11, 2026