Microbial adhesion and biofilm formation on various approved oral implants in situ

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00031685

Enrollment

Registered

2023-08-08

Start date

2023-04-01

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K10.9

Interventions

Group 1: 12 healthy volunteers of full age wear the splint system in three cycles of four hours, 24 hours and three days each during the study

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: • Written consent form. • Age: at least 18 years. • Good average health as assessed by the investigator. • Healthy teeth and periodontium. • Non-smoker

Exclusion criteria

Exclusion criteria: • Use of mouth rinses or antibiotics in the last 3 months. • Pregnancy and lactation. • Participation in another clinical trial, currently or within the last 30 days. • Gingivitis/periodontitis. • Smoker. • Dental caries. • Previous orthodontic treatment. • Systemic disease. • Autoimmune disease • Infections • Diabetes • Previous periodontal treatment. • Reflux esophagitis • Drug use

Design outcomes

Primary

Measure	Time frame
The primary endpoint is phenotypic and quantitative microbial characterization of initial microbial adhesion and biofilm formation on various oral implant materials in situ.	—

Secondary

Measure	Time frame
The secondary endpoint is the suitability of the implants for clinical use.	—

Countries

Germany

Contacts

Public ContactAli Al-Ahmad

Department für ZMK-Heilkunde

Ali.Al-Ahmad@uniklinik-freiburg.de0761 270-48940

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 14, 2026