Effects of Red Blood Cell Transfusions on Distant Metastases of Oral Squamous Cell Carcinomas

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00031677

Enrollment

610

Registered

2023-05-02

Start date

2021-02-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C14: Malignant neoplasm of other and vaguely defined localisations of the lip, oral cavity and pharynx C00-C14

Interventions

Group 1: Patients who have undergone surgery for primary oral squamous cell carcinoma are retrospectively analysed with regard to the distant metastasis rate, overall survival and progression-free sur

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Primary operated squamous cell carcinoma of the oral cavity, period of initial diagnosis 1.1.2000 - 31.12.2019.

Exclusion criteria

Exclusion criteria: Other tumour entities, second cancers, patients primarily irradiated or treated with chemotherapy, R1 status, no complete patient file, no regular participation in the follow-up programme (at least 12 months).

Design outcomes

Primary

Measure	Time frame
Rate of distant metastasis after tumour surgery in relation to allogeneic blood transfusions compared to other independent variables	—

Secondary

Measure	Time frame
Changes in overall survival and progression-free survival in relation to allogeneic blood transfusions compared to other independent variables.	—

Countries

Germany

Contacts

Public ContactLeonard Brandenburg

Universitätsklinikum Freiburg, Klinik für Mund-, Kiefer-, Gesichtsschirurgie Freiburg

leonard.brandenburg@uniklinik-freiburg.de0761 270-49160

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026