R77.80
Conditions
Interventions
Group 1: Prostatebiopsy with a combination of MRI-targeted biopsy + synchronous systematic biopsy according to a sectoral (SSB) AND perilesional template (PLT)
Sponsors
Universitätsklinikum Freiburg, Klinik für Urologie
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Men with indication for prostate biopsy and presence of an MRI-suspected lesion (PI-RADS > 3) - Age > 18 years - Presence of a written informed consent
Exclusion criteria
Exclusion criteria: - Very large index lesion suspicious for MRI (diameter > 40mm). - Previously diagnosed prostate carcinoma - Previous surgical therapy of the prostate (also due to a benign prostatic hyperplasia) - Anatomic abnormalities that preclude perineal biopsy of the prostate according to routine clinical practice
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - cancer detection rate of significant prostate cancer with the respective biopsy method (patient-level) - cancer detection rate of indolent prostate cancer with the respective biopsy method (patient-level) | — |
Secondary
| Measure | Time frame |
|---|---|
| - Cancer detection rates at lesion level. - Comparison of the number of biopsy cores (SSB vs. PLT) - Comparison of the percentage of cancerous cores (SSB vs. PLT) - Prospective evaluation of complications and functional aspects after perineal prostate biopsy | — |
Countries
Germany
Contacts
Public ContactAugust Sigle
Uniklinik Freiburg Klinik für Uroloogie
Outcome results
None listed