N95.1
Conditions
Interventions
Group 1: Healthy postmenopausal women (n = 33) aged 48 to 68 years with an average BMI of 25.2 kg/m2, supplemented with soy isoflavones (Soya Isoflavones Natures Aid, UK) 2 tablets for 3 days to reac
Sponsors
Polish Ministry of Science and Higher Education’s program “Regional Initiative Excellence” in the years 2019–2022
Eligibility
Sex/Gender
Female
Age
50 Years to 65 Years
Inclusion criteria
Inclusion criteria: Omnivorous healthy women after natural menopause, aged 50-65.
Exclusion criteria
Exclusion criteria: The study excluded women using unconventional diets, supplements containing phytoestrogens such as red clover and other soy isoflavones. The occurrence of an unnatural menopause - as a result of surgery or radiotherapy for cervical cancer. History of chronic diseases of the liver, thyroid, kidneys, gastrointestinal tract, cancer or allergy to soya, taking hormonal drugs, drugs that lower cholesterol or bile acid, bile acid sequestrants or statins. Exclusion was taking antibiotics or prebiotics in the three months preceding participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Level of isoflavones (daidzein (De), glysitein (Gle) and genistein (Ge)) and Equol in the urine samples Dietary composition determine by the ability to Eq production. | — |
Secondary
| Measure | Time frame |
|---|---|
| Level of isoflavones metabolites (Dihydrodaidzein (DHD) and O-Demethylangolensin (O-DMA)) and the level of urea nitrogen (UN), creatinine (Cr), sodium (Na), potassium (K), and magnesium (Mg) in the urine samples. | — |
Countries
Poland
Contacts
Public ContactJoanna Bajerska
Poznan University of Life Sciences
Outcome results
None listed