F44.5
Conditions
Interventions
Group 1: Patients with psychogenic, non-epileptic (dissociative) seizures (ICD-10 F44.5 / ICD-11 6B60. 4) will be interviewed regarding their experience of actual symptoms and carried out therapies a
Sponsors
Universitätsklinikum Bonn
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients with diagnoses in the field of neurotic, stress and somatoform disorders (ICD-10 F40-F48), personality and behavioral disorders (ICD-10 F60-F69) and/or behavioral and emotional disorders starting in childhood and youth (ICD-10 F90-F98). Previous proof of the corresponding disease by a video EEG examination (possibly as a diagnosis by exclusion).
Exclusion criteria
Exclusion criteria: Lack of ability to consent, acute suicidality, previous brain surgery. Certain infectious and parasitic diseases (ICD-10 A00-B99), malignant tumor diseases (ICD-10 C00-C97), organic mental disorders (ICD-10 F00-F09), mental and behavioral disorders caused by psychotropic substances (ICD-10 F10-F19 ), Schizophrenia, schizotypy and delusional disorders (ICD-10 F20-F29), intellectual disabilities (ICD-10 F70-F79), developmental disorders (ICD-10 F80-F89), systemic atrophies primarily affecting the central nervous system (ICD-10 G10-G14) , other degenerative diseases of the nervous system (ICD-10 G30-G32), cerebrovascular diseases (ICD-10 I60-I69), pregnancy, childbirth and childbirth (ICD-10 ICD-10 O00-O99).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patients are interviewed after initial diagnosis , based on an inhouse generated log sheet (Protokollbogen zum Erleben psychogener, nicht-epileptischer Anfälle im Behandlungsverlauf, PEB). They are openly asked about their subjective experience before, during and after psychogenic non-epileptic seizures. After that, patients are queried directly regarding intrusive memories, dissociative symptoms, emotions, cognitions/thoughts and bodily sensations. Additional questions concern seizure frequency, perceived trigger factors, intrusive memories and nightmares not associated with seizures, their actual concept of their disorder, the acceptance of the diagnosis and the presence of an actual/former psychiatric/psychosomatic or psychotherapeutic treatment. At further timepoints (after 3, 6 and 12 months) patients are questioned again on the perception of their seizures. Additionally, patients are interviewed regarding prescribed medication and details of carried out therapies, i.e. duration and modality (outpatient/(partial) inpatient), therapy school and applied techniques (e.g. trauma exposition). If traumatic memories have been treated, patients will be asked what kind of traumatic events occurred in their past (what category they belong to) and how often respective intrusive memories are still occurring. | — |
Secondary
| Measure | Time frame |
|---|---|
| At the above mentioned timepoints (T0, T1, T2, T3), the diagnostic status and symptom intensity of posttraumatic stress disorder will be assessed. To that end, the "Life-Events Checklist for DSM-5" (LEC-5, german version) as well as the "Posttraumatic Stress Disorder Checklist" (PCL-5, german version) or the "Clinician administered PTSD scale for DSM-5" (CAPS-interview, german version) will be applied. Furthermore, the "State-Trait Anger Expression Inventory-2" (STAXI-2, german version), the "Affective Style Questionnaire" (ASQ, german version) as well as the "State-Trait Anxiety Inventory" (STAI, german version) are used to assess anger expression, emotion regulation and anxiety . In addition, genetic and epigenetiv peculiarities of the population are to be determined, which is why a blood sample will be taken for genetic and epigenetic analysis. | — |
Countries
Germany
Contacts
Public ContactMax Christian Pensel
Universitätsklinikum Bonn
Outcome results
None listed