Investigation of the effects of heart failure with preserved ejection fraction (HFpEF) on cerebral small vessel disease

Investigation of the effects of heart failure with preserved ejection fraction (HFpEF) on cerebral small vessel disease - HIM-Study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00031583

Enrollment

102

Registered

2023-03-30

Start date

2023-04-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart failure with preserved ejection fraction (HFpEF)

Interventions

Group 1: HFpEF-patients and healthy controls HFpEF and healthy control subjects will be assessed with a broad test battery of structural and functional head MRI, neuropsychological testing, cardiac as

Eligibility

Sex/Gender

All

Age

50 Years to No maximum

Inclusion criteria

Inclusion criteria: HFpEF MRI suitable Arterial hypertension

Exclusion criteria

Exclusion criteria: MRI contraindication Dementia Depression

Design outcomes

Secondary

Measure	Time frame
Cognition, physical fitness, inflammatory biomarker, lifestyle factors	—

Primary

Measure	Time frame
CSVD in accordance to STIVE criteria	—

Countries

Germany

Contacts

Public ContactPatrick Müller

Universitätsklinikum Magdeburg, Klinik für Kardiologie und Angiologie

patrick.mueller@med.ovgu.de03916713201

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026