G20.11
Conditions
Interventions
Group 1: Patients with Parkinson's disease and STN-DBS performing part of the learning task once with deep brain stimulation turned on and once with it turned off.
Group 2: Healthy controls
Sponsors
Universitätsklinikum Leipzig, Neurologie
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: Specific to individuals with Parkinson's disease: Hoehn and Yahr stages 2 to 4 and condition after implantation of a deep brain stimulation system of STN and current therapy hereby
Exclusion criteria
Exclusion criteria: Alcohol/drug abuse (current or history). Other neurological disease with the exception of idiopathic Parkinson's syndrome. Depression ( BDI>19 points). Severe previous internal disease (e.g., heart failure) or orthopedic/rheumatologic disease. Inability to perform the experimental tasks. Pregnancy as per self-report. Relevant cognitive impairment (MOCA score < 18)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Angular error during the two adaptation conditions as well as in the de-adaptation condition. The angular error is defined as the difference between a straight line connecting the center cross to the target and a line connecting the center cross to the position of the cursor at maximum speed. | — |
Secondary
| Measure | Time frame |
|---|---|
| Reaction times and the movement times. | — |
Countries
Germany
Contacts
Public ContactJost-Julian Rumpf
Universitätsklinikum Leipzig, Neurologie
Outcome results
None listed