A randomized controlled trial to analyze the effects of an App-based patient education textbook (Ready4OP App) to increase health literacy before major oncologic surgery and its potential effects on surgical outcomes in Sweden, Slovenia, Spain, and Germany. The APERIO trial.

A randomized controlled trial to analyze the effects of an App-based patient education textbook (Ready4OP App) to increase health literacy before major oncologic surgery and its potential effects on surgical outcomes in Sweden, Slovenia, Spain, and Germany. The APERIO trial. - Aperio

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00031507

Enrollment

600

Registered

2023-05-22

Start date

2023-08-07

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgical oncology in the abdomen

Interventions

Group 1: Intervention with a specific patient education tool about preoperative optimization Group 2: Center specific treatment

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Written informed consent 2. Willing to participate 3. Patients before major surgical oncologic procedures* 4. Patients having a smartphone with Android or iOS

Exclusion criteria

Exclusion criteria: 1. Patients younger than 18 years 2. Women that are anamnestically pregnant 3. Patients unable to understand the rationale of the study 4. Patients unable to interact with the application 5. Patients with a planned palliative oncologic surgery 6. Patients with an ECOG performance status of 3 or higher 7. Patients with mental impairment leading to inability to cooperate 8. Patients under guardianship or imprisoned

Design outcomes

Primary

Measure	Time frame
To evaluate the efficacy of a patient education platform to modify health literacy and patient autonomy in patients before major oncologic surgery.	—

Secondary

Measure	Time frame
- To investigate mortality rates at 90 days - To evaluate compliance and adherence - To analyze the effects on surgical outcomes	—

Countries

Germany, Slovenia, Spain, Sweden

Contacts

Public ContactAndreas A. Schnitzbauer

Universitätsklinikum Frankfurt am Main

andreas.schnitzbauer@kgu.de+49-69-630187197

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 7, 2026