C25 C18 C20 C78.7
Conditions
Interventions
Group 1: Pancreatic cancer after curative treatment, prospective cohort, Doppler sonographic detection of occult liver metastasis after curatively treated pancreatic cancer by Doppler perfusion index.
Sponsors
Klinik am See
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. curatively (surgically with or without (neo)adjuvant therapy) treated carcinoma of the exocrine pancreas or colorectum. 2. ECOG 0 to 2, or "rehablitable". 3. age from 18 years
Exclusion criteria
Exclusion criteria: 1. evidence of metastasis (hepatic or extrahepatic). 2. severe liver parenchymal damage (cirrhosis from Child-Pugh stage A) 3. acute or chronic hepatitis infectious or non-infectious 4. severe (right) heart failure (NYHA III or higher) or evidence of a congested liver with pulsatility of the portal vein (RI greater than 0.5) 5. portal vein thrombosis, portal vein stenosis (threshold flow velocity 50cm/sec) or portal hypertension 6. age under 18 years 7. ECOG 3 or 4, or "not capable of rehabilitation".
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| This study investigates the association of DPI measured after surgery and (liver) metastasis free survival. The prognostic and predictive values of DPI in relation to the development of hepatic metastasis will be investigated. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. correlation of DPI and the preoperative and postoperative tumor markers CA 19-9 and CEA, other laboratory values: Alb, protein, BMI, or body surface area 2. analysis of the scatter of the measured values (inter-observer problem) | — |
Countries
Germany
Contacts
Public ContactChristian Lüders
Klinik am See
Outcome results
None listed