Overweight and obesity E65-E68
Conditions
Interventions
Group 1: 8-hour simulated working and learning situation (uninterrupted sitting
active control situation).
Group 2: 8-hour simulated working and learning situation (alternate sitting and standing
total standing time 2.5 hours per day)
Group 3: 8-hour simulated work and learning situation (continuous standing at a standing workdesk)
Group 4: 8-hour simulated work and learning situation (continu
Sponsors
Lehrstuhl Exercise Physiology and Metabolism
Eligibility
Sex/Gender
All
Age
18 Years to 29 Years
Inclusion criteria
Inclusion criteria: - Regular students (incl. doctoral studies) of the University of Bayreuth in the age range between 18-29 years (both age groups included), - Overweight/obese according to the World Health Organization (WHO) classification from a body mass index (BMI) of 25 kg/m2 (the study team reserves the right to exclude individuals with a BMI greater than 25 kg/m2 whose classification was due to increased muscle mass and no apparent overweight).
Exclusion criteria
Exclusion criteria: - Acute infection due to coronavirus disease (COVID-19). - Serious acute/chronic illnesses that preclude participation in the study in the judgment of the study medical team - Pregnant women or women who directly intend to become pregnant - (Orthopedic) limitations that militate against sitting, standing or walking over a duration of 8 hours
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The aim of the study is to investigate how a change in body position (alternate sitting and standing, walking or standing continuously) compared to uninterrupted sitting affects the mean 8-h glucose metabolism. For this purpose, capillary glucose measurements will be performed for each 8-hour intervention period before the start and every hour thereafter. On each intervention day, the subjects always receive the same standardized breakfast (one choice possible) and lunch (choice of microwave meals). | — |
Secondary
| Measure | Time frame |
|---|---|
| - To investigate the effect of a change in body position (alternate sitting and standing, walking or continuous standing) compared to uninterrupted sitting on certain pro-/antiinflammatory markers (TNF-alpha, IL-6, IL-10, hs-CRP). For this purpose, venous blood draws for cytokine analysis will be performed at each 8-hour intervention period before baseline, one hour after lunch, and after eight hours. - The aim is to investigate how a change in body position (alternate sitting and standing, walking, or continuous standing) compared with uninterrupted sitting affects mean 24-h glucose metabolism. For this purpose, capillary glucose measurements will be performed for each 8-hour intervention period before the start and every hour thereafter. On each intervention day, the subjects always receive the same standardized breakfast (one choice possible) and lunch (choice of microwave meals). Measurements following the intervention will be performed by the participants themselves via manual glucose measurement on the fingertip hourly until night rest, once during the night and again after getting up the next day using Contour next one. - The aim is to investigate the effect of a change in body position (alternate sitting and standing, walking or continuous standing) on 8-h heart rate variability (HRV) compared to uninterrupted sitting. Measurements on HRV will take place using Bittium Faros 180 Holter ECG. - To investigate the effect of changing body position (alternate sitting and standing, walking or continuous standing) on 24-h heart rate variability (HRV) compared to uninterrupted sitting. Measurements on HRV will take place using Bittium Faros 180 Holter ECG. - To investigate whether there is an association between general sedentary behavior and certain pro/antiinflammatory markers (TNF-alpha, IL-6, IL-10, hs-CRP). For this purpose, venous blood sampling for cytokine analysis will be performed during the screenings. - It will be investigated whether ther | — |
Countries
Germany
Contacts
Public ContactSascha Hoffmann
Arbeitsbereich Theorie und Praxis der Sportarten und Bewegungsfelder
Outcome results
None listed