Lipedema Lipedema, Stage I Lipedema, Stage II Lipedema, Stage III
Conditions
Interventions
Group 1: Characterization of the sensory phenotype of obese lipohyperplasia dolorosa (LiDo) patients using quantitative sensory testing during weight loss.
Group 2: Characterization of the sensory phe
Sponsors
Universität zu Köln
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Generally: female, age between 18-40 years, present signed and irrevoked informed consent. For LiDo patients for weight reduction: medical diagnosis Lipohyperplasia dolorosa (LiDo), coincident obesity BMI > 40, For the weight loss group: study-independent planned weight loss to achieve BMI 40.
Exclusion criteria
Exclusion criteria: Limitation of the ability to communicate (language barrier, cognitive barriers, ...). Diseases affecting the sensory nervous system (e.g. Parkinson's disease, multiple sclerosis, radiculopathy, injuries of nerves innervating the sensory area of different genesis, diabetic polyneuropathy, peripheral polyneuropathies of different genesis, etc.). skin stresses on the areas of measurement topical application of analgesics to the areas of measurement (e.g. plasters, creams, ...) diagnosed coagulation or wound healing disorder other known alteration in pain perception or another diagnosed pain disorder Liposuction already performed prior to study inclusion Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Characterization of the changes of the different sensory modalities in the clinical phenotype in female patients: QST profiles of all LiDo patients before and after substantial weight reduction. QST profiles of all LiDo patients before and after lymphological liposculpture. QST profiles of obese patients (independent of weight reduction or liposculpture). | — |
Secondary
| Measure | Time frame |
|---|---|
| The correlation of the primary outcome measures with the pain measures recorded in the pain questionnaire: German pain questionnaire of all patients Pain history questionnaire of all LiDo patients before and after weight reduction or liposuction | — |
Countries
Germany
Contacts
Public ContactRebecca Dinnendahl
Universitätsklinikum Köln
Outcome results
None listed