patients with Head and Neck carcinoma
Conditions
Interventions
Group 1: N=100
Head and neck tumor specimens for tissue sections
Group 2: N= 30
Samples from head and neck tumors for cell culture and tumor-slice culture experiments
Group 3: N = 30
Ex vivo observati
Sponsors
Universitätsklinikum Jena; Klinik für Hals-, Nasen- und Ohrenheilkunde
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Patients who have already undergone surgery for a head and neck tumor and who have written informed consent for the use of residual material, in which residual tumor tissue has been accrued and preserved or - Patients undergoing surgery for a head and neck tumor and who have accrued residual tumor tissue or - There is a signed informed consent from the patient for participation in the TROPHY study.
Exclusion criteria
Exclusion criteria: non
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proof-of-principle that this method is suitable for studying human tumor tissue | — |
Secondary
| Measure | Time frame |
|---|---|
| - to demonstrate that TROPHY imaging is suitable to describe specific characteristics of tumors and changes under therapy by morphochemical tissue and cell analysis - For this purpose, tissue from head and neck tumors is characterized using standard methods (histology, immunohistology, molecular diagnostics) and the results are compared with the results of TROPHY microscopy | — |
Countries
Germany
Contacts
Public ContactOrlando Guntinas-Lichius
Universitätsklinikum Jena, Klinik für Hals-, Nasen- und Ohrenheilkunde
Outcome results
None listed