Long/Post-COVID patients with cognitive fatigue
Conditions
Interventions
Group 1: frontal anodal tDCS (verum condition)
four sessions, 30 minutes each, 1.5mA over the left dlPFC
Group 2: frontal sham tDCS
four sessions, 30 minutes each
Sponsors
Otto-von-Guericke-Universität Magdeburg, med. Fakultät, Universitätsklinik für Neurologie, Sektion Neuropsychologie
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - cognitive fatigue (WeiMUS cognitive scale >= 17) - positive SARS-CoV-2-finding (COVID-19), at least 3 months old
Exclusion criteria
Exclusion criteria: - diagnose of depression or anxiety disorder, other psychiatric disorders - medication with antidepressants, opioids, anticonvulsants - neurological disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of subjective Fatigue (MFIS; total and subscales) through repetitive verum tDCS Assessment: Three or four days before the first stimulation session (pre), one day after the last stimulation session (post), one month after the last stimulation session (follow-up) | — |
Secondary
| Measure | Time frame |
|---|---|
| - Improvement of Quality of Life (EQ-5D-5L) - Improvement of subjective state fatigue (VAS) - Improvement of objective fatigability parameters (behavioral data) - Improvement of fatigability associated EEG-components: Alpha, Theta, P50 Assessment: Three or four days before the first stimulation session (pre), one day after the last stimulation session (post), one month after the last stimulation session (follow-up) | — |
Countries
Germany
Contacts
Public ContactMagdalena Mischke
Otto-von-Guericke-Universität Magdeburg, med. Fakultät, Universitätsklinik für Neurologie, Sektion Neuropsychologie
Outcome results
None listed