Comparison of regional anesthesia procedures used for perioperative analgesia during total knee arthroplasty regarding perioperative pain, mobilization, process times and complications: continuous sciatic nerve and continuous transsartorial saphenous nerve block with versus without fascia iliaca compartment single-shot block

Comparison of regional anesthesia procedures used for perioperative analgesia during total knee arthroplasty regarding perioperative pain, mobilization, process times and complications: continuous sciatic nerve and continuous transsartorial saphenous nerve block with versus without fascia iliaca compartment single-shot block - TKA w/ vs. w/o FICB

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00031288

Enrollment

Registered

2023-02-22

Start date

2023-03-13

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intra- and postoperative pain after total knee arthroplasty

Interventions

Group 1: Peripheral regional anesthesia: Continuous sciatic nerve block + Continuous transsartorial saphenous block + Fascia iliaca compartment block (FICB) Group 2: Peripheral regional anesthesia: Co

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Age = 18 y/o - Elective primary total knee arthroplasty at the study center - Consent to regional anesthesia procedure - Consent to participation in this study after a detailed explanation of an investigating physician

Exclusion criteria

Exclusion criteria: - Age 6 months, ongoing outpatient or inpatient pain treatment) - Previous endoprosthetic operation of the treated knee - Spinal anesthesia is the preferred procedure - Opioids in the premedication - Bleeding tendency

Design outcomes

Primary

Measure	Time frame
Pain (numeric rating scale, NRS) within the first 24h post operation, day 0	—

Secondary

Measure	Time frame
- Perioperative Pain (numeric rating scale, NRS): • day -1 (preop pain in rest/stress and maximum pain) • day 0 (pain at arrival/discharge from the PACU and maximum pain) • day 1 (cumulative pain during the day in rest/stress and maximum pain) • day 2 (cumulative pain during the day in rest/stress and maximum pain) • day 3 (cumulative pain during the day in rest/stress and maximum pain) - Perioperative process time • duration of RA implementation • duration of induction • Incision-to-suture-time • duration of anesthesia - Postoperative process time - Postoperative characteristics of the nerve block • temperature sensitivity • motor function • sensitivity in the area of the femoral and sciatic nerve - Postoperative need for analgesics • oral analgesics • intravenous analgesics • local anesthetic-loading rate and number of bolus administration - Postoperative RA-complications • malfunction of RA (no anesthesia in the target area) • dislocation of the catheter • obstruction of the catheter • local anesthetic leakage at the injection site • fall while on RA - further postoperative complications • PONV • delirium • shivering - Postoperative Mobilisation at postoperative days 1/2/3 • Stand and Walk (yes/no) • Timed Up and Go (TUG) Test • Range of motion knee (flexion and extension) •Quadriceps muscle function according to MRC	—

Measure

Time frame

- Perioperative Pain (numeric rating scale, NRS): • day -1 (preop pain in rest/stress and maximum pain) • day 0 (pain at arrival/discharge from the PACU and maximum pain) • day 1 (cumulative pain during the day in rest/stress and maximum pain) • day 2 (cumulative pain during the day in rest/stress and maximum pain) • day 3 (cumulative pain during the day in rest/stress and maximum pain) - Perioperative process time • duration of RA implementation • duration of induction • Incision-to-suture-time • duration of anesthesia - Postoperative process time - Postoperative characteristics of the nerve block • temperature sensitivity • motor function • sensitivity in the area of the femoral and sciatic nerve - Postoperative need for analgesics • oral analgesics • intravenous analgesics • local anesthetic-loading rate and number of bolus administration - Postoperative RA-complications • malfunction of RA (no anesthesia in the target area) • dislocation of the catheter • obstruction of the catheter • local anesthetic leakage at the injection site • fall while on RA - further postoperative complications • PONV • delirium • shivering - Postoperative Mobilisation at postoperative days 1/2/3 • Stand and Walk (yes/no) • Timed Up and Go (TUG) Test • Range of motion knee (flexion and extension) •Quadriceps muscle function according to MRC

—

Countries

Germany

Contacts

Public ContactBenedikt Büttner

Klinik für Anästhesiologie, Universitätsmedizin Göttinngen

benedikt.buettner@med.uni-goettingen.de+495513967766

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 11, 2026