Use of platelet rich fibrin (PRF) in the surgical closure of cleft palate

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00031246

Enrollment

Registered

2023-02-21

Start date

2020-01-08

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Q35.9

Interventions

Group 1: In the study group, in addition to the conventional palatal closure, a PRF membrane is inserted between the nasal and oral mucosa. Group 2: In the control group, the conventional palate closu

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: In order to be included in the study, the patient must present themselves to the clinic of the Clinic for Oral and Maxillofacial Surgery and fulfill the need for surgical closure of a cleft palate.

Exclusion criteria

Exclusion criteria: The exclusion criteria include inoperable patients, patients with systemic diseases (particularly diabetes or bleeding disorders), patients taking antibiotics or drugs that affect swelling or wound healing.

Design outcomes

Secondary

Measure	Time frame
Postoperative morbidity after palatal closure.	—

Primary

Measure	Time frame
Evaluation of whether a PRF membrane can help reduce residual oroantral fistulae after palatal closure.	—

Countries

Germany

Contacts

Public ContactMarie Sophie Katz

Uniklinik RWTH Aachen,Klinik für Mund-Kiefer- und Gesichtschirurgie

mkatz@ukaachen.de+492418088231

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026