Lipedema E88.2
Conditions
Interventions
Group 1: Clinical and anthropometric measurements as well as metabolic and laboratory analyses and imaging in patients with stages 1–4 lipedema.
Group 2: Control group: Clinical and anthropometric mea
Sponsors
UKR
Eligibility
Sex/Gender
Female
Age
16 Years to 99 Years
Inclusion criteria
Inclusion criteria: Lipedema St. 1-4 Control group: Women without a lipedema diagnosis, matched for age and BMI, without relevant chronic diseases.
Exclusion criteria
Exclusion criteria: Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Occurrence of edema in the legs, pressure pain, skin appearance, body fat percentage, weight, waist-hip ratio (WHR), circumference measurements, and comprehensive metabolic and lipoprotein analysis using NMR spectroscopy. Time of assessment: once at the start of the study (baseline). Measurement methods: clinical examination, anthropometric measurements, bioimpedance analysis, and NMR spectroscopy. | — |
Secondary
| Measure | Time frame |
|---|---|
| Depression tendency (PHQ-9) – Assessment at the start of the study using a standardized questionnaire (PHQ-9). LEFS (Lower Extremity Functional Scale) – Assessment at the start of the study using a validated questionnaire. Eating habits – Assessment at the start of the study using a standardized dietary questionnaire (e.g., FFQ). General health status – Survey at the start of the study using self-report (VAS) and medical assessment. Evaluation of fibrosis and fat content – Once at the start of the study using elastography and Controlled Attenuation Parameter (CAP). Evaluation of lipedema vascularization – once at the start of the study using color-coded duplex sonography, B-flow, and microvascular imaging (MVI). Dual-energy X-ray absorptiometry (DXA) – once at the start of the study to determine body composition. | — |
Countries
Germany
Contacts
Public ContactSally Kempa
UKR
Outcome results
None listed