Q15.0 Q12.0
Conditions
Interventions
Group 1: Children (<18 years) with primary congenital glaucoma (PCG)
Group 2: Children (<18 years) with juvenile open-angle glaucoma
Group 3: Children (<18 years) with secondary glaucoma following cat
Sponsors
Augenklinik und Poliklinik, Universitätsmedizin der Johannes Gutenberg-Universität Mainz
Eligibility
Sex/Gender
All
Age
No minimum to 17 Years
Inclusion criteria
Inclusion criteria: Presence of one of the following diagnoses: a) primary congenital glaucoma (PCG) b) juvenile open-angle glaucoma (JOAG) c) secondary glaucoma following lentectomy (aphakic glaucoma) d) secondary glaucoma due to anterior segment dysgenesis e) cataract (control group) - no previous surgery (except from lentectomy in case of aphakic glaucoma) - no other ocular or systemic pathologies - inclusion into the German Childhood Glaucoma Registry (ReCG) and additional informed consent of caregivers for substudy
Exclusion criteria
Exclusion criteria: - language barrier
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference in proteomic composition of aqueous humor (AH) in children with glaucoma compared to a control group (children with cataract) examined by liquid chromatography-mass spectrometry (LC-MS) prior to glaucoma or cataract surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| - Influence of clinical parameters such as intraocular pressure, corneal diameter, axial length, central corneal thickness, corneal findings, gonioscopic findings, funduscopic findings - Influence of genetic mutations (if available) | — |
Countries
Germany
Contacts
Public ContactEsther M. Hoffmann
Augenklinik und Poliklinik, Universitätsmedizin der Johannes Gutenberg-Universität Mainz
Outcome results
None listed