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Opportunistically determined bone mineral density: "Comparison of QCT-based bone mineral density with opportunistically determined bone mineral density in the spine"

Opportunistically determined bone mineral density: "Comparison of QCT-based bone mineral density with opportunistically determined bone mineral density in the spine" - Opportunistically determined bone mineral density

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00031221
Enrollment
500
Registered
2023-09-18
Start date
2023-11-23
Completion date
Unknown
Last updated
2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

M81.9

Interventions

Group 1: Patients with and without osteoporotic vertebral fracture who received CT of the spine and QCT for bone mineral densitometry as part of routine clinical practice (coverage period 2000-2022).

Sponsors

Institut für Neuroradiologie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. QCT and routine CT of the spine present 2. maximum time interval between QCT and routine CT of 30 days 3. all underlying diseases except multiple myeloma 4. at least one vertebral body from BWK 12 to LWK 4 present and measurable by both QCT and routine CT (i.e., no fracture, no foreign material/cement within the vertebral body) 5. for routine CT, either the raw data set (axial with max. slice thickness of 1 mm) and/or a sagittal reconstruction of the spine bony is available (sagittal with max. slice thickness of 3 mm)

Exclusion criteria

Exclusion criteria: 1. Age under 18 years 2. Incomplete examination data

Design outcomes

Primary

MeasureTime frame
Evaluation of the utility of artificial intelligence analysis for opportunistic determination of volumetric bone mineral density and comparison to QCT-based measurements in the spine

Secondary

MeasureTime frame
1. To gain knowledge of the utility of algorithm-based opportunistic volumetric bone mineral density measurements compared to QCT-based volumetric bone mineral density values for differentiating between patients with vs. without vertebral fractures. 2. To analyze how the results of algorithm-based imaging data analysis differ from manual measurements by radiologists.

Countries

Germany

Contacts

Public ContactAlexandra Gersing

Institut für Neuroradiologie

alexandra.gersing@med.uni-muenchen.de+4989440072501

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026