Analgesia concepts in ECMO patients: A retrospective comparison of patients with COVID-19-associated ARDS versus a pre-pandemic ARDS patient population.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00031216

Enrollment

239

Registered

2023-02-06

Start date

2023-04-01

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

J80.0

Interventions

Group 1: Correlation of COVID-19-associated ARDS with mortality and delirium incidence and the type and dosage of analgesics +/- muscle relaxants used in a retrospective analysis of a 170-patient data

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Major diagnosis "adult severe respiratory distress syndrome - ARDS". Need for invasive mechanical ventilation and veno-venous extracorporeal membrane oxygenation therapy (ECMO therapy)

Exclusion criteria

Exclusion criteria: lack of ARDS veno-arterial ECMO

Design outcomes

Primary

Measure	Time frame
Are there differences in mortality and delirium incidence in patients with SARS-CoV-2-associated ARDS and need for ECMO therapy versus non-SARS-CoV-2-associated ARDS and ECMO therapy depending on the type and dosage of analgesics and sedatives and muscle relaxants used.	—

Secondary

Measure	Time frame
Does the SARS-CoV-2 virus variant influence the type and dosage of analgesics and sedatives used? Can implications for future pandemics be derived from the results of the primary research question? Cluster analysis based question - Can machine learning cluster analysis identify risk groups and does the cause of ARDS (COVID vs. non-COVID) play a critical role? - Are there subgroups within the collective of ARDS patients that differ in their mortality and complication risk from the other ARDS patients included?	—

Measure

Time frame

Does the SARS-CoV-2 virus variant influence the type and dosage of analgesics and sedatives used? Can implications for future pandemics be derived from the results of the primary research question? Cluster analysis based question - Can machine learning cluster analysis identify risk groups and does the cause of ARDS (COVID vs. non-COVID) play a critical role? - Are there subgroups within the collective of ARDS patients that differ in their mortality and complication risk from the other ARDS patients included?

—

Countries

Germany

Contacts

Public ContactBenedikt Schick

Klinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Ulm

benedikt.schick@uniklinik-ulm.de+4973150060001

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 14, 2026