Rhythm of the Night - Study: Energy Drinks and Alcohol - Acute Cardiovascular Effects in Young, Healthy Adults

Rhythm of the Night - Study: Energy Drinks and Alcohol - Acute Cardiovascular Effects in Young, Healthy Adults - Rhythm of the Night

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00031179

Enrollment

Registered

2023-02-01

Start date

2024-02-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I51.6

Interventions

Group 1: Young, healthy adults will consume 750 mL energy drink (= 240mg caffeine) mixed with 120 mL vodka (=38,4 g alcohol). Group 2: Young, healthy adults will consume 750 mL placebo mixed with 120

Eligibility

Sex/Gender

All

Age

18 Years to 29 Years

Inclusion criteria

Inclusion criteria: No preexisting health conditions

Exclusion criteria

Exclusion criteria: Diseases of the cardiovascular system (e.g. cardiac arrhythmias, high blood pressure, heart failure), metabolic diseases (e.g. hyperthyroidism, disorders of sugar metabolism), BMI =25 kg/m2, diseases of the kidneys and liver, diseases of the central nervous system, mental illnesses, nicotine consumption, regular drug intake including the consumption of alcohol, participants who take medication on a regular basis and which have an effect on the cardiovascular function (exception: oral contraceptives), sudden cardiac death within the family history, pregnancy.

Design outcomes

Primary

Measure	Time frame
Systolic blood pressure, diastolic blood pressure, QTc, number of supraventricular extrasystoles and ventricular extrasystoles. The primary endpoints will be measured at baseline, 30, 60, 120, and 240 minutes after beverage consumption on each study day.	—

Secondary

Measure	Time frame
The following parameters are measured at the beginning, as well as 30, 60, 120 and 240 minutes after drinking on each study day: central systolic blood pressure, central diastolic blood pressure, augmentation index averaged to a heart rate of 75 bpm, pulse wave velocity , stroke volume, heart rate, cardiac output, systemic vascular resistance based on central venous pressure and blood pressure input, ICON variation, systolic time ratio (PEP/LVET), contractility index, cardiac performance index, thoracic fluid content, stroke volume variation, corrected flow time, oxygen supply and breath alcohol.	—

Measure

Time frame

The following parameters are measured at the beginning, as well as 30, 60, 120 and 240 minutes after drinking on each study day: central systolic blood pressure, central diastolic blood pressure, augmentation index averaged to a heart rate of 75 bpm, pulse wave velocity , stroke volume, heart rate, cardiac output, systemic vascular resistance based on central venous pressure and blood pressure input, ICON variation, systolic time ratio (PEP/LVET), contractility index, cardiac performance index, thoracic fluid content, stroke volume variation, corrected flow time, oxygen supply and breath alcohol.

—

Countries

Germany

Contacts

Public ContactFelix Sebastian Oberhoffer

Division of Pediatric Cardiology and Intensive Care, University Hospital, LMU Munich, Munich, Germany

Felix.Oberhoffer@med.uni-muenchen.de+49 89 4400 73941

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026