G80
Conditions
Interventions
Group 1: CP group: diagnosed with infantile cerebral palsy with resultant spasticity of the lower extremities.
Group 2: Control group: healthy individuals matched for gender, age, and height to partic
Sponsors
Deutsches Zentrum für Luft- und Raumfahrt - Institut für Luft- und Raumfahrtmedizin, Muskel- und Knochenstoffwechsel
Eligibility
Sex/Gender
All
Age
12 Years to 18 Years
Inclusion criteria
Inclusion criteria: - CP group: diagnosed with infantile cerebral palsy with resulting spasticity of the lower extremities. - Control group: healthy individuals matched for gender, age, and height to participants in the CP group. All groups: - Age: 12-18 years - Ability to consent - Consent and signed informed consent prior to the study.
Exclusion criteria
Exclusion criteria: - Limitations of mobility that prevent 90° positions of the ankle joints and knees - Injuries or illnesses in the past six weeks that interfere with calf muscle contractions or the jump and hop test
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Feasibility of three different active muscle tests (maximal isometric contraction, controlled building-up and breaking-down isometric contraction, constant submaximal isometric contraction), defined as the number of successfully completed muscle tests per subject in both groups. | — |
Secondary
| Measure | Time frame |
|---|---|
| - Feasibility of isometric muscle contractions of the plantar flexors, defined as duration and constancy of contraction measured by dynamometry. - Repeatability of the muscle architectural parameters fascicle length, pinna angle, muscle thickness, and fascicle curvature of the medial gastrocnemius, using B-mode ultrasound at rest and during dynamic isometric contractions - Repeatability of the indirect stiffness parameter shear wave velocity of the medial gastrocnemius by shear wave elastography at rest and during constant isometric contractions - Repeatability of the generated torque of the plantar flexors by means of dynamometry - Acceptability of the performed tests by means of questionnaire | — |
Countries
Germany
Contacts
Public ContactJörn Rittweger
Deutsches Zentrum für Luft- und Raumfahrt (DLR) - Institut für Luft- und Raumfahrtmedizin, Muskel- und Knochenstoffwechsel
Outcome results
None listed