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Optimizing intermittent theta burst stimulation (iTBS) in humans. A randomized controlled cross-over pilot study.

Optimizing intermittent theta burst stimulation (iTBS) in humans. A randomized controlled cross-over pilot study. - Opti-iTBS

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00031090
Enrollment
10
Registered
2023-08-31
Start date
2023-11-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

There will be no diseases/health issues examined.

Interventions

Group 1: Real intermittent theta burst stimulation (iTBS) with 600 pulses Group 2: Sham iTBS with 600 pulses Group 3: Real iTBS with 900 pulses Group 4: Sham iTBS with 900 pulses

Sponsors

Abteilung für Neuroanatomie, Institut für Anatomie und Zellbiologie, Albert-Ludwigs-Universität Freiburg
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: - Normal or corrected-to-normal vision - Voluntary consent in written form after having received oral and written information about the study - Right-handed

Exclusion criteria

Exclusion criteria: - Persons who are unwilling to be informed of potential incidental findings - Participants who do not provide their consent for sharing their de-identified and pseudonymized data - Pregnancy, planned pregnancy or breastfeeding - Brain pathology - Non-removable metal objects in or at the body (e.g. heart pacemakers) - Neurological disorder or injury (e.g. epilepsy) - Psychiatric disorders (e.g. substance use disorder) - Intake of centrally active medication (e.g. antidepressants) - Tattoo that is non-compatible with the MRI - Claustrophobia - Surgery in the head, neck or chest area - Acute illness or infection during the preceding 4 weeks

Design outcomes

Primary

MeasureTime frame
Motor evoked potential amplitudes measured from a small hand muscle.

Secondary

MeasureTime frame
Resting motor threshold, active motor threshold, self-reports, physiological biomarkers.

Countries

Germany

Contacts

Public ContactAndreas Vlachos

Abteilung für Neuroanatomie, Institut für Anatomie und Zellbiologie, Albert-Ludwigs-Universität Freiburg

vlachos@anat.uni-freiburg.de+49 761 203 5056

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026