Molecular characterization of staphylococcal adaptation during asymptomatic colonization and infection.

Molecular characterization of staphylococcal adaptation during asymptomatic colonization and infection. - Adaptation of staphylococci during colonization and infection

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00031078

Enrollment

Registered

2023-01-17

Start date

2024-04-08

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

L20

Interventions

Group 1: For the study, swabs will be taken from the nasal mucosa and skin/abscess of patients with atopic dermatitis or an abscess.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with atopic dermatitis or an abscess who have lesional skin sites and agree with the study protocol. Healthy volunteers will be included in the study as a control group.

Exclusion criteria

Exclusion criteria: No consent from the patient or legal guardian. Likewise, patients with coagulation disorders or anticoagulation are excluded.

Design outcomes

Primary

Measure	Time frame
The aim of the study is to investigate the adaptation of staphylococci depending on habitat/lifestyle (asymptomatic in the nasal mucosa versus infectious on the skin). This will clarify whether there is a consistent gene expression pattern for colonization and infection and which virulence factors are activated on the skin.	—

Countries

Germany

Contacts

Public ContactAmir Yazdi

Uniklinik RWTH Aachen - Klinik für Dermatologie und Allergologie - Hautklinik

hautklinik-chefsekretariat@ukaachende+40 241 75010

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 11, 2026