C00-C97
Conditions
Interventions
Group 1: Transcranial electrical stimulation of the mortor cortex of cancer patients with pain.
Group 2: Transcranial electrical stimulation of the dorsolateral prefrontal cortex of cancer patients wi
Sponsors
Universitätsmedizin Göttingen
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: -Adult subjects = 18 years old. -Able to provide informed consent to participate in the study. -Able to self-report pain. -To have a diagnosis of cancer affecting lung, breast, pancreas or colon (with metastases or not). -The life expectancy of at least six months. -Cancer pain persisting despite best tolerated pharmacological treatment -Pain rated >= 5 on a 0-10 Numeric Rating Scale (NRS) persisting for over 1 month prior to enrolment. -Ability to use internet and WhatsApp or have a person (relative, caregiver) to help them.
Exclusion criteria
Exclusion criteria: -Pregnant women or women of fertile age that did not have efficacious contraception during the whole period of the study. -Neurological or psychiatric diseases (except anxiety or depression) -Unstable medical conditions (e.g., uncontrolled diabetes, uncompensated cardiac issues, heart failure or chronic obstructive pulmonary disease). -History of neurosurgery, traumatic brain injury with loss of consciousness, and/or cortical lesions -Present risk factors for receiving tES (e.g., history of epilepsy, metal devices in the brain, etc.). -History of non-malignant chronic pain.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Numeric rating scale of the intensity of pain | — |
Secondary
| Measure | Time frame |
|---|---|
| -Use of analgesic medication (type and dose) -NRS of unpleasantness of pain -NRS of interference due to pain -NRS of fatigue | — |
Countries
Germany, Israel, Romania, Spain, Switzerland
Contacts
Public ContactAndrea Antal
Universitätsmedizin Göttingen
Outcome results
None listed