Prospective Study on the epileptogenicity of white matter lesions

Prospective Study on the epileptogenicity of white matter lesions - WML-EPI 1

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00031052

Enrollment

120

Registered

2023-01-10

Start date

2023-03-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G40.9

Interventions

Group 1: Patients with first unprovoked seizure and cerebral small vessel disease (CSVD) Group 2: Patients with first unprovoked seizure and no cerebral small vessel disease (CSVD)

Eligibility

Sex/Gender

All

Age

60 Years to No maximum

Inclusion criteria

Inclusion criteria: - Patients with first seizure - Patients with MRI of the head - age > 59 years

Exclusion criteria

Exclusion criteria: - epileptogenic lesion in the MRI - patients unable to provide informed consent

Design outcomes

Primary

Measure	Time frame
Reccurent unprovoked seizure within 12 months after first unprovoked seizure	—

Secondary

Measure	Time frame
Amount and localization of white matter lesions	—

Countries

Germany

Contacts

Public ContactMartin Holtkamp

Charité Universitätsmedizin Berlin

martin.holtkamp@charite.de+49 30 450 560 560

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026