An open-label-placebo RCT for improving psychological distress in highly stressed students: The impact of pharmaceutical form and simulated side effects

An open-label-placebo RCT for improving psychological distress in highly stressed students: The impact of pharmaceutical form and simulated side effects - EDMONT_OLP_FIELD

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00030987

Enrollment

180

Registered

2023-01-02

Start date

2020-09-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

perceived stress

Interventions

Group 1: Placebo nasal spray active for 7 days Group 2: Placebo nasal spray passive for 7 days Group 3: Placebo capsule passive for 7 days Group 4: No intervention (7 days natural history)

Eligibility

Sex/Gender

All

Age

18 Years to 69 Years

Inclusion criteria

Inclusion criteria: German speaking stress level (PSS-10 > 20)

Exclusion criteria

Exclusion criteria: allergies against ingredients of Placebo severe asthma

Design outcomes

Primary

Measure	Time frame
Change in stress (PSS-10) from baseline to day 8 of participation	—

Secondary

Measure	Time frame
Change in psychological distress (DASS-21) from baseline to day 8 of participation	—

Countries

Germany

Contacts

Public ContactAlexander Winkler

Abt. Klinische Psychologie und Psychotherapie der Justus-Liebig-Universität Gießen

Alexander.Winkler@psychol.uni-giessen.de+49 641 99-26084

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 11, 2026